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In theory, random distribution should preferentially engage cross-reactive B cells that can cross-recognize multiple versions of RBD/spike proteins next to each other on the nanoparticle

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This review explores the molecular interplay between chronic infections and host immunity, highlights next-generation nanomaterials for regenerative applications, and proposes a sustainable paradigm that bridges clinical effectiveness with environmental responsibility

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doi:10.1016/j.nut.2016.12.018 5 Richie JP Jr, et al